Interpreting Tuberculin Skin Tests in a Population With a High Prevalence of HIV, Tuberculosis, and Nonspecific Tuberculin Sensitivity

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Interpreting Tuberculin Skin Tests in a Population With a High Prevalence of HIV, Tuberculosis, and Nonspecific Tuberculin Sensitivity

Understanding the epidemiology and clinical course of tuberculosis is hampered by the absence of a perfect test for latent tuberculosis infection. The tuberculin skin test (TST) is widely used but suffers poor specificity in those receiving the bacille Calmette-Guérin vaccine and poor sensitivity in individuals with human immunodeficiency virus (HIV) infections. TST responses for a target popul...

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Practice of Epidemiology Interpreting Tuberculin Skin Tests in a Population With a High Prevalence of HIV, Tuberculosis, and Nonspecific Tuberculin Sensitivity

a The Author 2010. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the or...

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Seven of twenty-eight (25%) patients with untreated tuberculosis had skin induration of less than 6 mm to one tuberculin unit (TU), and 3 (11%) to 10 TU PPD. Among twenty-four patients with lung disease, there were no detectable differences in radiological extent of disease between reactors and non-reactors to low-dose tuberculin. However, non-reactors were significantly more malnourished (P le...

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ژورنال

عنوان ژورنال: American Journal of Epidemiology

سال: 2010

ISSN: 0002-9262,1476-6256

DOI: 10.1093/aje/kwq017